CA 125 – RMab

For In Vitro Diagnostic Use

CA-125 reacts with malignant ovarian epithelial cells. CA-125 also reacts with antigens in Seminal Vesicle Carcinoma and Anaplastic Lymphoma.
In adult tissues, CA-125 is found in epithelial cells of Fallopian tube, endometrium and endocervix, pancreas, colon, gall bladder, stomach, kidney, apocrine sweat gland, and mammary gland. It is also found in mesothe- lial cell lining of pleura, pericardium and peritoneum. It is found in ovarian tumors of serous, endometrioid or clear-cell types and Adenocarcinomas of Mullerian type.

Antibody Type Rabbit Monoclonal
Clone EP48
Isotype IgG
Reactivity Paraffin, Frozen
Localization Membranous, Cytoplasmic
Control Colon, Pancreas, Epitheliod Mesothelioma, Ovarian Carcinoma

CA-125 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.