CD4 – RMab

For In Vitro Diagnostic Use

CD4 is a glycoprotein expressed on the surface of T-helper cells, regulatory T-cells, monocytes, macrophages, and dendritic cells. On T-cells, CD4 is the co-receptor for the T-cell receptor (TCR). It amplifies the signal gener-ated by the TCR by recruiting the tyrosine kinase that is essential for activating many molecules involved in the signaling cascade of an activated T-cell. CD4 antigen is involved in the recognition of Type II Major Histocompatability Complex antigens (MHC-II). CD4 is also the receptor for Human Immunodeficiency Virus (HIV). It is present on most T-helper cells and normal thymocytes.

Antibody Type Rabbit Monoclonal
Clone RBT-CD4
Isotype IgG
Reactivity Paraffin, Frozen
Localization Membranous
Control Tonsil, Lymph Node

CD4 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.