CD5 – RMab

For In Vitro Diagnostic Use

CD5 is a glycoprotein monomer with an MW of 67 kDa belonging to the scavenger receptor cysteine-rich (SRCR) family of extracellular domain-like structures, and it possesses a large cytoplasmic domain suitable for signal transduction. CD5 is a T-cell marker that also reacts with a range of neoplastic B-cells, e.g., B-cell Chronic Lymphocytic Leukemia (B-CLL), B-cell Small Lymphocytic Lymphoma (B-SLL), and Mantle Cell Lymphoma. CD5 is expressed in T-lymphocyte subsets and is modulated during cellular activation; however, it does not react with granulocytes or monocytes.

Antibody Type Rabbit Monoclonal
Clone RBT-CD5
Isotype IgG
Reactivity Paraffin, Frozen
Localization Membranous
Control Tonsil, Lymph Node

CD5 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.