CD61 – MMab

For In Vitro Diagnostic Use

CD61 is a glycoprotein found on megakaryocytes (bone marrow cells), platelets and their precursors. CD61 antigen plays a role in platelet aggregation and also as a receptor for fibrinogen, fibronectin, von Willebrand factor and vitronectrin. CD61 labels the IIIa subunit of the noncovalently-linked glycoprotein heterodimer IIb/IIIa complex present on human platelets and their precursors. This antibody is useful in identifying megakaryoblastic differentiation as seen in Megakaryoblastic Leukemia.

Antibody Type Mouse Monoclonal
Clone 2f2
Isotype IgG1/K
Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Bone Marrow

CD61 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.