HER-2 neu – RBT HER2 – RMab

For In Vitro Diagnostic Use

HER-2 neu (also known as c-erbB-2) is a member of the epidermal growth factor receptor (EGFR) family and is notable for its role in the pathogenesis of breast cancer and as a target of treatment. It is a cell membrane surface-bound tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. HER-2 neu is a proto-oncogene located at the long arm of human chromosome 17(17q11.2-q12).

Antibody Type: Rabbit Monoclonal
Clone: RBT-HER2
Isotype: IgG
Reactivity: Paraffin, Frozen
Localization: Membranous
Control: Breast Carcinoma

HER2/neu is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.