IgA – MMab

For In Vitro Diagnostic Use

Immunoglobulin A (IgA) is the main immunoglobulin in mucous secretions, including tears, saliva, and colostrum, as well as respiratory, intestinal, prostatic, and vaginal secretions. It is also found in small amounts in blood. Because it is resistant to degradation by enzymes, secretory IgA provides protection against microbes proliferating in body secretions, especially those of the digestive and respiratory tracts. IgA antibody reacts with surface immunoglobulin IgA alpha chains. It is extremely useful when identifying Acute Leukemias, IgA Myelomas, Plasmacytomas, and B-cell lineage derived Hodgkin’s Lymphomas. However, due to the restricted expression of heavy and light chains in these diseases, demonstration of B-cell Lymphomas is possible with clonal gene-rearrangement studies.

Antibody Type: Mouse Monoclonal
Clone: BSB-39
Isotype: IgG1/K
Reactivity: Paraffin, Frozen
Localization: Cytoplasmic
Control: Tonsil, Lymph Node, Spleen, Kidney, Colon

IgA is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.