TintoFast Androgen Receptor (BSB-4), MMab

For Mohs In Vitro Diagnostic Use

The main function of the androgen receptor is as a DNA-binding transcription factor which regulates gene expression. However, the androgen receptor has additional functions independent of DNA binding. The AR signaling pathway plays a key role in development and function of male reproductive organs, including the prostate and epididymis. AR also plays a role in nonreproductive organs, such as muscle, hair follicles, and the brain.

TintoFast Androgen Receptor antibody reacts with the androgen receptor and also with the newly-described A form of the receptor. This antibody does not cross-react with estrogen, progesterone or glucocorticoid receptors. Abnormalities in the AR-signaling pathway have been linked to a number of diseases, including Prostate Cancer, Kennedy’s Disease and male infertility.

Antibody Type Mouse Monoclonal
Clone BSB-4
Isotype IgG1 Reactivity
Paraffin, Frozen
Localization Nuclear
Control Prostate, Prostatic Adenocarcinoma

TintoFast Androgen Receptor is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.