TintoFast p63 (4A4), MMab

Name: TintoFast p63 (4A4), MMab
Brand: LABS-Laboratory Advanced Business Solutions
SKU: BSB-3698-3
Price: 389.0 USD
Availability: InStock

In addition to p53, mammalian cells contain two homologous genes, p63 and p73. These genes give rise to the expression of proteins that are highly similar to p53 in structure and function

Prediluted:

Ready-to-Use: 3.0 mL Ready-to-Use: 7.0 mL Ready-to-Use: 15.0 mL

Variant

$389.00

Intended Use

For Mohs In Vitro Diagnostic Use

Summary and Explanation

In particular, p63 and p73 proteins can induce p53-responsive genes and elicit programmed cell death. p73 and p63 are important during development and differentiation. In particular, p63
appears to be primarily implicated in epithelial development. Anti-p63 to human p63 protein labels an epitope common to all six p63 isotypes (TAp63α, TAp63β, TAp63γ, ΔNp63α, ΔNp63β, ΔNp63γ).TintoFast p63 labels the nuclei of myoepithelial cells in the prostate gland as well as breast tissue, making it useful in differentiating benign vs. malignant prostate lesions and breast lesions.

Antibody Type: Mouse Monoclonal
Clone: 4A4
Isotype: IgG2a/K
Reactivity: Paraffin, Frozen
Localization: Nuclear
Control: Prostate, Breast, Skin, Salivary Gland

Presentation

TintoFast p63 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

TintoFast p63 (4A4), MMab

$389.00