TintoFast SOX-10 (BSB-62), MMab

For Mohs In Vitro Diagnostic Use

It acts as a marker for neuroendocrine cells. Synaptophysin reacts with Neuroendocrine cells of human Adrenal Medulla, Carotid Body, Skin, Pituitary, Thyroid, Lung, Pancreas and Gastrointestinal mucosa. Positive staining is seen in neurons of the Brain, Spinal Cord, Retina, and Paneth’s cells in the Gastrointestinal tract and Gastric parietal cells.

The TintoFast Synaptophysin antibody identifies normal Neuroendocrine cells and Neuroendocrine neoplasms. Diffuse, finely-granular cytoplasmic staining is observed and probably correlates with the distribution of the antigen within Neurosecretory vesicles. The expression of Synaptophysin is independent of the presence of NSE or other Neuroendocrine markers. Synaptophysin is an independent broad-range marker of neural and neuroendocrine differentiation.

Antibody Type: Rabbit Polyclonal
Clone: Polyclonal
Isotype: IgG
Reactivity: Paraffin, Frozen
Localization: Cytoplasmic
Control: Pancreas, Brain, Pituitary, Adrenal, Colon

TintoFast Synaptophysin is a rabbit polyclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.