TintoFast PRAME (RBT-PRAME), RMab

For Mohs In Vitro Diagnostic Use

Podoplanin is specifically expressed in the endothelium of lymphatic capillaries but not in the blood vasculature. In normal skin and kidney, podoplanin is co-localized with VEGFR3/FLT4, another marker for lymphatic endothelial cells.

TintoFast Podoplanin antibody is selectively expressed in lymphatic endothelium as well as Lymphangiomas, Kaposi’s Sarcomas and in subset Angiosarcomas with probable lymphatic differentiation. Podoplanin has also been shown to be expressed in Epithelioid Mesotheliomas, Hemangioblastomas and Seminomas.

Antibody Type: Mouse Monoclonal
Clone: D2- 40
Isotype: IgG1
Reactivity: Paraffin, Frozen
Localization: Cytoplasmic, Membranous
Control: Tonsil, Lymph Node, Lymphangioma

TintoFast Podoplanin is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.